FIGURE

Fig. S5

ID

ZDB-FIG-190731-14

Publication

Rueda et al., 2019 - The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming

Other Figures

All Figure Page

Back to All Figure Page

Fig. S5

Schematic of the core Hippo signaling pathway and the consequence of YAP5SA expressed by the Yap5SA transgenic mouse (A) . Expression of the Yap5SA transgene in the adult mouse retina (B) . The transgene, indicated by GFP, is primarily expressed in the ONL. However, we observed mosaic expression among the MGs in the INL that was confirmed by SOX2 immunofluorescence (see inset from boxed region in B) . Upon tamoxifen injection (IP), YAP5SA (detected with an anti-FLAG antibody) is expressed in a subset of MGs that also express LacZ from the transgene’s IRES-LacZ cassette (C) . N = 3 per group. ONL = outer nuclear layer, INL = inner nuclear layer, GCL = ganglion cell layer

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Rep.