FIGURE

Figure 5—figure supplement 1.

ID
ZDB-FIG-190723-1069
Publication
Carretero-Ortega et al., 2019 - GIPC proteins negatively modulate Plexind1 signaling during vascular development
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Figure 5—figure supplement 1.

Penetrance and expressivity of Se-DLAV truncations in <italic>gipc1<sup>skt1(MZ)</sup></italic> and <italic>gipc1<sup>skt1(MZ)</sup>; plxnd1<sup>fov01b</sup>/+</italic> embryos at 32 hpf.

(A) Penetrance bar graph. Percentage of embryos of the indicated genotypes with Se-DLAV truncations (gray; a summation of the ‘minimal,’ ‘moderate,’ and ‘maximal’ categories) and with non-truncated Se-DLAV (black; ‘full’ category). The distributions of these two phenotypic classes were statistically significantly different between gipc1skt1(MZ) and gipc1skt1(MZ); plxnd1fov01b/+ embryos as assessed by a two-sided Fisher Exact test, p=0.0361. (B) Expressivity bar graph. Percentage of ‘maximal’ (red), ‘moderate’ (yellow), and ‘minimal’ (gray) Se-DLAV truncations and of ‘full’ (black) non-truncated Se-DLAV in embryos with Se-DLAV truncations of the indicated genotypes. The distributions of these four phenotypic classes were statistically significantly different between gipc1skt1(MZ) and gipc1skt1(MZ); plxnd1fov01b/+ embryos (brackets and asterisks) as assessed by a two-sided Fisher Exact test, p=0.00004. For additional supplementary information related to this figure, see Supplementary file 6. This figure is related to Figure 5.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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