FIGURE

Fig. 6

ID

ZDB-FIG-190711-25

Publication

Cianciolo Cosentino et al., 2019 - Moderate Nucleoporin 133 deficiency leads to glomerular damage in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Glomerular filtration is impaired in nup133 morphants. Representative images of cross sections of 4 dpf control (left panels) and nup133 morphants larvae (right panels) fixed 20 minutes after injection of Alexa Fluor™ 647 conjugated-BSA into the common cardinal vein. Lower panels represent a higher magnification view of the proximal tubule region (dotted lines). Note the uptake of fluorescent BSA in the apical endosomes of the proximal tubules of the Nup133-depleted larva (arrows). Scale bars 50 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-nup133 + MO3-nup133
Knockdown Reagents:	MO2-nup133 MO3-nup133
Observed In:	glomerular filtration
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.