FIGURE
Fig. 7
- ID
- ZDB-FIG-190709-14
- Publication
- O'Connor et al., 2018 - Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino
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Fig. 7
Morphological development of craniofacial features in the developing zebrafish probed by CyHQ-gad1b-ccMO. (A,B) Control fish. (B) Alcian blue stained, flat mount preparation showing normal development of Meckel’s (m), basihyal (bh), and palatoquadrate (pq) cartilages. (C,D) The gad1b morphant fish exhibit reduced Meckel’s and basihyal cartilages (denoted with brackets) with midlines defects. Note irregular organization of the cells in the Meckel’s cartilage of gad1b morphant fish (asterisk in D and H) compared to controls or ccMO injected fish photoactivated at 1 dpf.
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
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| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Days 7-13 |
Phenotype Detail
Acknowledgments
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Full text @ ACS Chem. Neurosci.