FIGURE

Fig. S5

ID

ZDB-FIG-190530-19

Publication

Konjikusic et al., 2018 - Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development

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Fig. S5

Immunofluorescence (IF) of Kif6 mutant multiciliated tissues in mouse and zebrafish.

(A-B) Immunofluorescence of trachea sections in Kif6^p.G555fs/+ and Kif6^p.G555fs mice showing no apparent cilia defects present in trachea of Kif6 mutant mice. Acetylated tubulin (green) marking cilia, DAPI-stained nuclei (magenta) (C-D) Representative IF of zebrafish nasal pit cilia shows typical cilia in kif6 mutant zebrafish to wildtype counterparts. Acetylated tubulin (magenta) marking cilia, gamma-tubulin marking basal bodies (green). Scale bars are 20μM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kif6^gw326/gw326
Observed In:	olfactory pit cilium
Stage:	Adult

Phenotype Detail

Acknowledgments

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