FIGURE

Fig. 8

ID

ZDB-FIG-190325-12

Publication

Visetsouk et al., 2018 - Basal epithelial tissue folding is mediated by differential regulation of microtubules

Other Figures

All Figure Page

Back to All Figure Page

Fig. 8

Microtubule filament stability is required for JNK-mediated basal anisotropic cell shape. (A-D) Digital slices from z-series images of memGFP-injected wild-type embryos treated at 16 ss with DMSO (A,B) or SP600125 (C,D). Embryos were then treated at 18 ss with DMSO (A,C) or paclitaxel (B,D) and imaged at 24 ss. MHBC cells are outlined in yellow. (E) Quantification of anisotropic cell shape. All basal x:z ratios were compared post-hoc with the SP600125/DMSO treatment. Boxplots indicate the 25th and 75th percentiles and the median. Four independent experiments are represented. DMSO/DMSO n=6; DMSO/paclitaxel n=6; SP600125/DMSO n=10; SP600125/paclitaxel n=7. *P<0.05, ***P<0.005. Scale bars: 10 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development