FIGURE

Fig. S2

ID

ZDB-FIG-190129-4

Publication

Liu et al., 2017 - Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting

Other Figures

All Figure Page

Back to All Figure Page

Fig. S2

Stable transgenic zebrafish lines showing in vivo enhancer activities patterns of E2 and E3 in different development stages.

In 5hpf, F2 embryos of Tg(E2:GFP) exhibit universal enhancer activity (a, b). In 30 hpf, F2 embryos of Tg(E2:GFP) exhibit GFP activity in the forebrain (c, d), and F2 embryos of Tg(E3:GFP) exhibit GFP activity in central nervous system (h, i). In 72 hpf, F2 embryos of Tg(E2:GFP) exhibit GFP activity in lower jaw, otic vesicle, head epidermis and forebrain (e, f), and F2 embryos of Tg(E3:GFP) exhibit GFP activity in lower jaw and head epidermis (j, k). In 96hpf, sagittal section of F2 embryos of Tg(E2:GFP) (g) showing in vivo activity of E2 in oral epithelium (o.e.), ethmoid plate (e.p.) and head epidermis (epi), and sagittal section of F2 embryos of Tg(E3:GFP) (l) showing in vivo activity of E3 in oral epithelium, ethmoid plate, head epidermis and heart. Scale bar =100μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.