FIGURE

Fig. 3

ID

ZDB-FIG-190129-3

Publication

Liu et al., 2017 - Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting

Other Figures

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Fig. 3

Stable transgenic zebrafish lines showing in vivo enhancer activities patterns of E2 and E3 in craniofacial region.

(a,b) Z-stacks from confocal imaging of live stable (F1) transgenic GFP-reporter lines for (a) E2 and (b) E3 at 4?d.p.f. (representative of F1 lines from at least three independent F0 founders). Arrows indicate GFP expression in ventral epithelium and oral epithelium. White dashed lines in a,b indicate section planes in c?f, respectively. (c?f) Transverse sections (12??m) of stable GFP-reporter lines of E2 (c,e) and E3 (d,f) show in vivo activity of E2 in head epidermis, retina (r), lens (l), ethmoid plate (e.p.), oral epithelium (o.e., white arrow), brain (br) and palatoquadrate (pq). Scale bars=100??m.

Expression Data

Gene:	EGFP
Fish:	ui103Tg ui104Tg
Anatomical Terms:	brain ethmoid cartilage lens oral epithelium palatoquadrate cartilage retina (all 6)
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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