ZFIN ID: ZDB-FIG-181116-61
Haller et al., 2018 - A missense variant in SLC39A8 is associated with severe idiopathic scoliosis. Nature communications   9:4171 Full text @ Nat. Commun.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Adult

Fig. S3

Additional Images of abnormal slc39a8 KO zebrafish after alizarin red staining at 12 weeks post-fertilization. (A) A single mutant slc39a8 zebrafish demonstrating spinal fusion by fluorescent or light microscopy. (B) Various skeletal abnormalities were observed among slc39a8 KO zebrafish including fused vertebrae and abnormal bone growth along the spine (4 different fish shown). Shown are homozygous mutant slc39a8 zebrafish produced from a cross between two heterozygous mutant slc39a8 zebrafish and genotyped for the mutation. Scale bar 2mm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
slc39a8stl583/stl583(AB) standard conditions Adult caudal vertebra fused with caudal vertebra, abnormal
Adult caudal vertebra malformed, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Nature communications for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Nat. Commun.