FIGURE
Fig. 4
- ID
- ZDB-FIG-181022-5
- Publication
- Lawrence et al., 2018 - The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function, which leads to early-onset osteoarthritis.
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Fig. 4
Shape changes in col11a2 zebrafish mutants have a greater effect on jaw biomechanics than material property changes. (a,b) FE models of maximum (EMax) and minimum (EMin) principal strain during mouth opening in 7 dpf wt and col11a2−/− zebrafish. Red arrowheads, areas of high strain; black arrowheads, areas of low strain; black asterisks, jaw joint. (a) wt jaw shape with wt material properties and col11a2−/− shape with col11a2−/− material properties. (b) wt shape with col11a2−/− material properties and col11a2−/− shape with wt material properties. Ventral and lateral views shown for each condition. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Phil. Trans. Roy. Soc. Lond., Series B