FIGURE
Fig. S1
- ID
- ZDB-FIG-180822-35
- Publication
- Schultz et al., 2018 - Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation
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Fig. S1
Histological analysis of neoplastic populations in TALEN induced rb1-brain tumor T3 and T4 is consistent with primitive neuroectodermal-like tumor. H&E stained sections of tissue remaining after dissection of tumors T3 (A, B) and T4 (C, D) used for transcriptome analysis. Sections exhibit an unencapsulated, multifocally infiltrative neoplastic population within the neuropil. Neoplastic cells are small with deeply basophilic, round to oval to wedge-shaped nuclei, densely clumped chromatin, and scant amounts of cytoplasm. Scale bars A, C 200μm; B, D 50 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Dis. Model. Mech.