FIGURE
Fig. S7
- ID
- ZDB-FIG-180822-36
- Publication
- Schultz et al., 2018 - Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation
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Fig. S7
Ectopic M-phase phosphohistone-H3 positive cells in the telencephalon/forebrain and hindbrain of rb1D7/D7 mutant 5 dpf larva. A wildtype +/+ and B rb1D7/D7 mutant 5 dpf gross morphology. C-J Cryosections were labeled with antibodies to the neuronal marker HuC/D (red) and mitotic M-phase marker phosphohistone-H3 (green). Sections through the telencephalon (C-F) and hindbrain (G-J) show that in wild type mitotic cells are absent or rare, but in the rb1D7/D7 mutant many ectopic phosphohistone-H3 positive cells are scattered throughout the region containing HuC/D-positive cell bodies of neurons. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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