FIGURE

Fig. 4

ID
ZDB-FIG-180803-11
Publication
Liu et al., 2018 - Rare copy number variants analysis identifies novel candidate genes in heterotaxy syndrome patients with congenital heart defects
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Fig. 4

Analysis of pitx2 and lefty2 expression patterns in the lateral plate mesoderm in 18?22 somites. a The expression of pitx2 exhibits four patterns, left, right, bilateral, or absent, in the posterior lateral plate mesoderm of zebrafish embryos. b Morphants show left, right, bilateral or absent lefty2 expression in the cardiac field. c, d Summary of abnormal pitx2 and lefty2 mRNA expression in zebrafish morphants. e, f Summary of abnormal pitx2 and lefty2 mRNA expression in zebrafish with mRNA over-expressed. Embryos are viewed dorsally with anterior to the top. Bars show the percent of abnormal pitx2 and lefty2 expression including three types: right, bilateral, absent expression. Standard control (StdCtrl or Std-RNA) is negative control. galnt11 is used as positive control. Error bars represent the SEM. *P <?0.05, **P <?0.01, ***P <?0.001, respectively, vs. standard control
Expression Data
Genes:
Fish: (all 6)
Knockdown Reagents: (all 6)
Anatomical Terms:
Stage Range: 14-19 somites to 20-25 somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish: (all 6)
Knockdown Reagents: (all 6)
Observed In:
Stage Range: 14-19 somites to 20-25 somites

Phenotype Detail
Acknowledgments
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