ZFIN Figure: Takaki et al., 2018, Fig. 3

ZFIN ID: ZDB-FIG-180703-9

ZFIN ID: ZDB-FIG-180703-9

Takaki et al., 2018 - A zebrafish model for ocular tuberculosis. PLoS One 13:e0194982 Full text @ PLoS One

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	WT
Condition:	bacterial treatment by injection: Mycobacterium marinum M
Observed In:	eye
Stage:	Adult

Fig. 3

Anatomical localization of intraocular granuloma after M. marinum infection.

(A) Schematic representation showing localization of granulomas near the retinal vasculature (arrowhead), and in retinal pigment epithelium-choroid complex (dotted circle). (B) Localization of intraocular granulomas (within dotted regions); in the outer eye of zebrafish larvae corresponding to the retinal pigment epithelium-choroid complex, and in the choroid in human ocular TB. (C) Localization of perivascular infection (arrowheads); as seen as bacterial aggregates in close association of blood vessels in zebrafish, and retinal periphlebitis associated with focal chorioretinitis overlying the blood vessel in human ocular TB. (B-C) Confocal images of ocular infection in Tg(mpeg:YFP) and Tg(kdrl:dsRed2) zebrafish, and fundus photographs of human ocular TB. Scale bars, 25 μm and 750 μm, respectively.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT	bacterial treatment by injection: Mycobacterium marinum M	Adult	eye inflamed, abnormal

Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One