ZFIN ID: ZDB-FIG-180703-9
Takaki et al., 2018 - A zebrafish model for ocular tuberculosis. PLoS One   13:e0194982 Full text @ PLoS One
Observed In:
Stage: Adult

Fig. 3

Anatomical localization of intraocular granuloma after M. marinum infection.

(A) Schematic representation showing localization of granulomas near the retinal vasculature (arrowhead), and in retinal pigment epithelium-choroid complex (dotted circle). (B) Localization of intraocular granulomas (within dotted regions); in the outer eye of zebrafish larvae corresponding to the retinal pigment epithelium-choroid complex, and in the choroid in human ocular TB. (C) Localization of perivascular infection (arrowheads); as seen as bacterial aggregates in close association of blood vessels in zebrafish, and retinal periphlebitis associated with focal chorioretinitis overlying the blood vessel in human ocular TB. (B-C) Confocal images of ocular infection in Tg(mpeg:YFP) and Tg(kdrl:dsRed2) zebrafish, and fundus photographs of human ocular TB. Scale bars, 25 μm and 750 μm, respectively.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT bacterial treatment by injection: Mycobacterium marinum M Adult eye inflamed, abnormal
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