FIGURE

Fig. S2

ID

ZDB-FIG-180608-16

Publication

Lai et al., 2018 - The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish

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Fig. S2

Reduction in the number of EdU+ cardiomyocytes in wwtr1^-/-hearts at 96 hpf.

96 hpf WT (A) and mutant (B) heats stained for EdU after 16 hours of incubation (80-96 hpf). myl7:EGFP-Hsa.HRAS and myl7:nlsDsRed expression lavel cardiomyocyte membranes and nuclei, respectively. Yellow arrows point to EdU+ compact layer cardiomyocytes. Yellow arrowheads point to EdU+ trabecular layer cardiomyocytes. Scale bar, 20 μm. (C) Quantification of EdU+ cardiomyocytes in the outer curvature of the ventricle in WT and mutant hearts. (D) Quantification of EdU+ cardiomyocytes in the compact and trabecular layers in WT and mutant hearts. Error Bars are one unit of standard deviation . P-Values were calculated by Student's t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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