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General Information
ZIRC
ZFIN ID: ZDB-FIG-180507-4
Shi et al., 2017 - Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?. Molecular and cellular biochemistry   433(1-2):97-102 Full text @ Mol. Cell. Biochem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Term:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
il1b twu34Tg control Protruding-mouth heart RTPCR
twu34Tg chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
twu34Tg + MO1-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
twu34Tg + MO2-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
Luciferase bw6Tg standard conditions Protruding-mouth heart IFL
bw6Tg chemical treatment by environment: aristolochic acid Protruding-mouth heart IFL
bw6Tg + MO1-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart IFL
bw6Tg + MO2-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart IFL
ptgs2b twu34Tg control Protruding-mouth heart RTPCR
twu34Tg chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
twu34Tg + MO1-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
twu34Tg + MO2-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
bw6Tg chemical treatment by environment: aristolochic acid Protruding-mouth heart Luciferase expression increased amount, abnormal
bw6Tg + MO1-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart Luciferase expression amount, ameliorated
bw6Tg + MO2-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart Luciferase expression amount, ameliorated
twu34Tg chemical treatment by environment: aristolochic acid Protruding-mouth heart edematous, abnormal
Protruding-mouth heart ptgs2b expression increased amount, abnormal
Protruding-mouth heart il1b expression increased amount, abnormal
Protruding-mouth heart morphology, abnormal
Protruding-mouth heart looping disrupted, abnormal
twu34Tg + MO1-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart ptgs2b expression amount, ameliorated
Protruding-mouth heart il1b expression amount, ameliorated
Protruding-mouth heart morphology, ameliorated
twu34Tg + MO2-slc5a2 chemical treatment by environment: aristolochic acid Protruding-mouth heart ptgs2b expression amount, ameliorated
Protruding-mouth heart il1b expression amount, ameliorated
Full text @ Mol. Cell. Biochem.