Gene

ptgs2b

ID
ZDB-GENE-041014-323
Name
prostaglandin-endoperoxide synthase 2b
Symbol
ptgs2b Nomenclature History
Previous Names
  • Cox-2b (1)
  • si:dkey-97o5.6
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Exhibits peroxidase activity. Involved in cellular response to organic cyclic compound. Predicted to localize to endoplasmic reticulum membrane. Is expressed in several structures, including gonad; heart; kidney; male organism; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; artery disease (multiple); arthritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptgs2b Human Ortholog
No data available
Associated With ptgs2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Family IPR019791 Haem peroxidase, animal-type
Family IPR029576 Prostaglandin G/H synthase 2
Homologous_superfamily IPR010255 Haem peroxidase superfamily
Homologous_superfamily IPR037120 Haem peroxidase domain superfamily, animal type
Domain Details Per Protein
Protein Length EGF-like domain Haem peroxidase, animal-type Haem peroxidase domain superfamily, animal type Haem peroxidase superfamily Prostaglandin G/H synthase 2
UniProtKB:Q5RI06 606
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations