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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-180412-22
Rambeau et al., 2017 - Reduced aggrecan expression affects cardiac outflow tract development in zebrafish and is associated with bicuspid aortic valve disease in humans. International Journal of Cardiology   249:340-343 Full text @ Int. J. Cardiol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagent:
Anatomical Term:
Stage: Day 4
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
acana WT standard conditions Day 4 bulbus arteriosus ISH
WT chemical treatment by environment: ruthenium red Day 4 bulbus arteriosus ISH
WT + MO1-tnnt2a standard conditions Day 4 Not Detected bulbus arteriosus ISH
acanb WT standard conditions Day 4 Not Detected bulbus arteriosus ISH
elnb WT standard conditions Day 4 bulbus arteriosus ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + CRISPR1-acana standard conditions Protruding-mouth atrium increased size, abnormal
Protruding-mouth heart edematous, abnormal
Protruding-mouth heart development disrupted, abnormal
WT + MO2-acana standard conditions Protruding-mouth atrium increased size, abnormal
Protruding-mouth heart edematous, abnormal
Protruding-mouth heart development disrupted, abnormal
Full text @ Int. J. Cardiol.