FIGURE

Fig. s3

ID

ZDB-FIG-180404-14

Publication

Lagendijk et al., 2017 - Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

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Fig. s3

Gross phenotypes in kdr/kdrl morphant and SL327 treated embryos (a) Venus expression (grey) from Tg(ve-cad:ve-cadTS) in the trunk of an un-injected control (uic) and a kdr/kdrl MO injected embryo at 3 dpf showing a loss of intersegmental vessels (ISVs) in the morphant (asterisks). Scale bar = 10μm. (b) Venus expression (grey) at 3 dpf from Tg(ve-cad:ve-cadTS) in 1%DMSO treated control and SL327 (4μM/1%DMSO) treated embryos. Treatment from 20 hpf till 3 dpf. SL327 treatment results in only mild intersegmental vessel defects (compared to kdr/kdrl knockdown (a)) recognized by thin ISVs (black arrowhead). Scale bar = 10μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.