FIGURE

Fig. s7

ID
ZDB-FIG-180320-31
Publication
Kim et al., 2017 - Ottogi Inhibits Wnt/?-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8
Other Figures
(all 15)
All Figure Page
Back to All Figure Page
Fig. s7

OTG inhibits reporter expression in TOPdGFP transgenic zebrafish

Views from animal pole, dorsal is to the right. Patterns of GFP reporter expression in control (A, 10/10, 100%), human OTG mRNA-injected (B, 12/13, 92%), zebrafish otg mRNA- injected (C, 12/14, 86%), or otg MO-injected (D, 18/20, 90%) embryo at shield stage (6 hpf). E-H. OTG overexpression suppresses whereas otg knockdown enhances Wnt8-induced reporter expression. TOPdGFP transgenic embryos were injected with indicated combination of wnt8 (7/7, 100%), human OTG (8/10, 80%), zebrafish otg mRNAs (6/10, 60%) and zebrafish otg morpholino (MO, 14/16, 87%). GFP reporter expression is examined by in situ hybridization.

Expression Data
Gene:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Shield

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Shield

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.