FIGURE

Fig. 5

ID

ZDB-FIG-180202-20

Publication

Farwell et al., 2017 - Novel Heparin Receptor Transmembrane Protein 184a Regulates Angiogenesis in the Adult Zebrafish Caudal Fin

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Fig. 5

Tmem184a knockdown results in increased endothelial cell proliferation. (A) Example confocal image projecting the third and fourth 4 dpa fin rays. The white circle highlights a point where fluorescence from GFP (green, ECs) H3P (red, Cy3 secondary antibody) overlap and look yellow. Zooming in on this point and rotating in a few different directions confirms nuclear H3P in an EC. (B) Quantitation of H3P/Fli1 ECs in the third and fourth fin rays of 4 dpa standard control, ATG, and SS MO-injected fins compared to third and fourth fin rays of the uninjected side. Graphs are shown as mean percent similarity ± S.E.M. **p < 0.01 compared to control. Data are representative of more than three independent experiments with at least four fish per experimental group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO1-tmem184a y1Tg + MO2-tmem184a
Condition:	amputation: caudal fin
Knockdown Reagents:	MO1-tmem184a MO2-tmem184a
Observed In:	regenerating fin endothelial cell proliferation
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Physiol.