FIGURE
Fig. 3
- ID
- ZDB-FIG-180103-39
- Publication
- Yan et al., 2017 - RETRACTED: Chemical inhibition reveals differential requirements of signaling pathways in krasV12- and Myc-induced liver tumors in transgenic zebrafish.
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Fig. 3
Effect of inhibition of Hedgehog signaling pathway on krasV12- and Myc-induced liver enlargement. 7?dpf fabp10+, kras+ or Myc+ larvae were treated with either 10??M cyclopamine or 1??M GANT61 in the presence of 10??g/ml Dox and 2D liver size was measured based on images. (A?C) Representative images of 7?dpf fabp10+ control larvae. (D?F) Representative images of 7?dpf kras+ larvae. (G?I) Representative images of 7?dpf Myc+ larvae. (J) Quantification of liver sizes for kras+ larvae. (K) Quantification of liver sizes for Myc+ larvae. N?=?20 from each groups; statistical significance: *p?<?0.05, Scale bar?=?20??m. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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