FIGURE

Fig. 5

ID

ZDB-FIG-171117-5

Publication

Lee et al., 2016 - Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration

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Fig. 5

Neuromast SCs with different capacities in HC regeneration and proliferation.

Hybrid larvae of pou4f3:GFP and ET20 fish ablated in HCs only (A,D), HC/fgfr1a(+) SCs (B,E), or HC/fgfr1a(-) SCs (C,F) were stained with HCS1 (A-C) or BrdU (D-F) antibody, to illustrate proliferating (BrdU⁺) and regenerated HCs (HCS1⁺). (G) Quantification showed that only HC/fgfr1a(+) SC ablation significantly reduced the regenerated HCs. (H) Quantification showed that HC/fgfr1a(+) SC ablation increased the number of proliferating cells; whereas HC/fgfr1a(-) SC ablation reduced the proliferating cells. (G,H) ***p<0.001; *p<0.05. n = 12 in each group. Scale bars: 10 μm.

Expression Data

Antibody:	Ab1-otof
Fish:	s356tTg; sqet20Et
Conditions:	light ablation: neuromast hair cell light ablation: neuromast hair cell
Anatomical Term:	neuromast hair cell
Stage:	Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s356tTg; sqet20Et
Conditions:	light ablation: neuromast hair cell light ablation: neuromast hair cell
Observed In:	neuromast hair cell
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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