FIGURE

Fig. 3

ID

ZDB-FIG-171113-31

Publication

Powell et al., 2016 - Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons

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Fig. 3

Injury paradigms stimulate regenerative response signatures that exhibit both commonality and uniqueness.

Fish were given an intraperitoneal injection of BrdU at 2 dpi and then sacrificed at 2 dpi (3 hours post BrdU injection), 4, 7, 14 and 30 dpi. (A–C) BrdU+ nuclei were counted and the percentage of BrdU+ nuclei residing in the (A) ONL, (B) INL and (C) GCL was determined for individual samples for each injury model. Data represents means ± s.d. (n ≥ 3). *P < 0.04549. (D–I) Representative images of retinal sections analyzed in (A–C) that were immunostained for BrdU at (D–F) 2 dpi or (G–I) 30 dpi following (D,G) needle poke, (E,H) PA or (F–I) NMDA injury. Scale bar is equal to 50 μm. Abbreviations are as in Fig. 1.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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