FIGURE

Fig. 1

ID

ZDB-FIG-171113-29

Publication

Powell et al., 2016 - Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons

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Fig. 1

Injury models generate unique cell death signatures.

(A) Representative images of retinal sections showing TUNEL detection (red) of apoptotic neuronal cell death 1 day following needle poke, UV light photoablation (PA), and NMDA neurotoxic injuries. (B) Relative localization of TUNEL+ nuclei by nuclear layer in the various injury models at 1 dpi. (C) Representative images of retinal sections showing TUNEL detection of apoptotic neuronal cell death at 1, 4 and 7 days following needle poke (single injury/retina), UV light photoablation, and NMDA neurotoxic injuries. (D) Quantification of TUNEL+ cells by nuclear layer in the various injury models at 1, 4 and 7 dpi. Data represents means ± s.d. (n = 4). Scale bar is equal to 50 μm. ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer; PA, photoablation; dpi, days post injury.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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