Fig. 4
- ID
- ZDB-FIG-170908-11
- Publication
- Breau et al., 2017 - Extrinsic mechanical forces mediate retrograde axon extension in a developing neuronal circuit
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Effects of Colcemid, Blebbistatin and Rockout treatments on OP morphogenesis. a Colcemid-treated ngn1:gfp embryos do not show any defects in OP morphogenesis at 24 s, as compared with DMSO controls. b Quantification of OP length and width at 24 s, in colcemid-treated embryos and DMSO controls. c Blebbistatin-treated ngn1:gfp embryos exhibit longer and thinner OPs at 24 s as compared with DMSO controls. d Quantification of OP length and width at 24 s in blebbistatin-treated embryos and DMSO controls. e ngn1:gfp embryos treated with Rockout show morphogenesis defects that are similar to those of blebbistatin-treated embryos. f Quantification of OP length and width at 24 s in embryos incubated with Rockout or DMSO. n indicates the number of analysed placodes (one placode per embryo) in each condition. p values: unpaired two-tailed t-tests. Scale bar: 50 µm |