FIGURE

Fig. 2

ID

ZDB-FIG-170609-9

Publication

Thyme et al., 2016 - Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development

Other Figures

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Fig. 2

Figure 2. Polq Is Required for Survival following DSBs Induced by Ionizing Radiation

(A) Survival rates and fraction of deformed embryos observed for MZpolq and WT embryos exposed to varying levels of ionizing radiation at three stages of early development (n = 14–32 for each condition). These data were collected at ∼24 hpf.

(B) Examples of observed deformities in MZpolq embryos compared with wild-type embryos subjected to the same levels of radiation. Additional examples are available in Figure S2D.

(C) Survival rate observed for MZpolq and wild-type embryos exposed to varying levels of UV radiation at the shield stage of development. The experiment was performed two to four times per condition, with n = 14–54 each time.

See also Figure S2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	polq^a153/a153 (AB/TL)
Condition:	gamma ray
Observed In:	whole organism
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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