FIGURE

Fig. 6

ID

ZDB-FIG-170606-24

Publication

Yoo et al., 2017 - Mind Bomb-Binding Partner RanBP9 Plays a Contributory Role in Retinal Development

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Fig. 6

Defects in the brain and retina of ranbp9-MO injected zebrafish embryos.

(A) Control (Cont) and ranbp9-MO injected (MO) zebrafish larvae at 5 dpf. Compared to normal development of body trunk region, reduced size of brain and eye was observed in the MO injected larva. Asterisk indicates swim-bladder. (B) By acridine orange staining, a specific cell death was detected in the brain tectum of 54 hpf morphants. (C) Disruption of retinal development in ranbp9 morphant. Section of HE-stained retina in control and ranbp9 morphant at 73 hpf. In wild-type, the retina was established into several layers; 1, ganglion cell layer: 2, inner plexiform layer: 3, inner nuclear layer: 4, outer plexiform layer: 5, outer nuclear layer: and 6, photoreceptor cell layer, respectively. In morphants, however, these layer formations were not well established.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-ranbp9
Knockdown Reagent:	MO1-ranbp9
Observed In:	brain optic tectum apoptotic process retina cell retina layer formation swim bladder trunk
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

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