FIGURE

Fig. 3

ID
ZDB-FIG-170428-28
Publication
El-Rass et al., 2017 - Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly.
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Fig. 3

Pdgfra homozygous mutants exhibit abnormal cardiac phenotypes. An incross of the pdgfra gene-trapped strain carrying a Tg(cmlc2:EGFP) transgene was used to investigate the cardiac phenotype. (A) At 48?hpf, mild and severe ?/? mutants present with abnormal cardiac looping; severe ?/? embryos also develop an enlarged atrium and pericardial edema. (B) At 96?hpf, the hearts of mild ?/? mutants remain incompletely looped, while severe ?/? mutants present with collapsed chambers and pericardial edema. Arrows pointing at ventricle (V) and atrium (A). The fish cranium is on the left. Scale bar: 100??m.
Expression Data
Gene:
Fish:
Anatomical Term:
Stage Range: Long-pec to Day 4

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage Range: Long-pec to Day 4

Phenotype Detail
Acknowledgments
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