FIGURE

Fig. 7

ID

ZDB-FIG-170428-10

Publication

Granneman et al., 2017 - Lipid droplet biology and evolution illuminated by the characterization of a novel Perilipin in teleost fish

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Fig. 7

Loss of Plin6 function impairs CB aggregation in adult zebrafish xanthophores.

(A?A?) An isolated scale from a wild-type animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (A) or forskolin-IBMX (A?) induced CB aggregation and dispersion, respectively. (B?B?) An isolated scale from a plin6 mutant animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (B) failed to induce tight CB aggregation (arrows). However, incubation in forskolin-IBMX (B?) induced CB dispersion. (E) Quantification of the aggregate diameter of wild-type and plin6 mutant xanthophores from measurements of Epinephrine-treated scales (N = 3; p=0.017).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	plin6^wsu2/wsu2
Observed In:	xanthophore carotenoid vesicle
Stage:	Adult

Phenotype Detail

Acknowledgments

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