FIGURE

Fig. 7

ID

ZDB-FIG-170428-10

Publication

Granneman et al., 2017 - Lipid droplet biology and evolution illuminated by the characterization of a novel Perilipin in teleost fish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Loss of Plin6 function impairs CB aggregation in adult zebrafish xanthophores.

(A–A’) An isolated scale from a wild-type animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (A) or forskolin-IBMX (A’) induced CB aggregation and dispersion, respectively. (B–B’) An isolated scale from a plin6 mutant animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (B) failed to induce tight CB aggregation (arrows). However, incubation in forskolin-IBMX (B’) induced CB dispersion. (E) Quantification of the aggregate diameter of wild-type and plin6 mutant xanthophores from measurements of Epinephrine-treated scales (N = 3; p=0.017).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	plin6^wsu2/wsu2
Observed In:	xanthophore carotenoid vesicle
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife