ZFIN Image: Granneman et al., 2017, Fig. 7

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Figure Caption

Fig. 7

Loss of Plin6 function impairs CB aggregation in adult zebrafish xanthophores.

(A–A’) An isolated scale from a wild-type animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (A) or forskolin-IBMX (A’) induced CB aggregation and dispersion, respectively. (B–B’) An isolated scale from a plin6 mutant animal showing xanthophore carotenoid body auto-fluorescence. 1 hr incubation in Epinephrine (B) failed to induce tight CB aggregation (arrows). However, incubation in forskolin-IBMX (B’) induced CB dispersion. (E) Quantification of the aggregate diameter of wild-type and plin6 mutant xanthophores from measurements of Epinephrine-treated scales (N = 3; p=0.017).

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Phenotype details

Acknowledgments

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