ZFIN ID: ZDB-FIG-170420-9
Zhu et al., 2017 - Vegfa Impacts Early Myocardium Development in Zebrafish. International Journal of Molecular Sciences   18(2) Full text @ Int. J. Mol. Sci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. 2

vegfaa regulates heart development in a dose-dependent manner. (A–I) Fluorescence micrographs of the hearts of wild-type (A–C), vegfaa morphants with moderate defects (D–F), and severe defects (G–I) at 96 hpf in the background of Tg(myl7:mCherry)/Tg(kdrl:EGFP) transgenic fish, Scale bar: 50 μm; (J) Statistical analysis of MO dosage and heart malformation in vegfaa morphants.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP la116Tg ; sd7Tg control Day 4 endocardium IHC
la116Tg ; sd7Tg + MO9-vegfaa control Day 4 endocardium IHC
mCherry la116Tg ; sd7Tg control Day 4 myocardium IHC
la116Tg ; sd7Tg + MO9-vegfaa control Day 4 myocardium IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
la116Tg ; sd7Tg + MO9-vegfaa control Day 4 heart hypotrophic, abnormal
Day 4 heart linear, abnormal
Day 4 heart tube formation decreased occurrence, abnormal
Day 4 heart valve malformed, abnormal
Day 4 heart valve trabecular, abnormal
Acknowledgments:
ZFIN wishes to thank the journal International Journal of Molecular Sciences for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Int. J. Mol. Sci.