FIGURE

Fig. 6

ID

ZDB-FIG-170301-19

Publication

Nam et al., 2017 - Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish

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Fig. 6

The effects of β-cyclodextrin included in compound K (CD-CK) and CK (compound K) with diazoxide (DZ) in alloxan-induced pancreatic islet-damaged zebrafish. (A) The size change in the pancreatic islets in each group. (B) Fluorescence intensity analysis in the pancreatic islets of the zebrafish. (C) Representative final pancreatic islet images of the normal (NOR), alloxan (AX), DZ, CK, CK with DZ, CD-CK, and CD-CK with DZ groups. Pancreatic islets are stained with 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose. The white arrow indicates the location of pancreatic islet. Scale bar = 100 μm. ^##p < 0.01, ^###p < 0.001 compared to normal. * p < 0.05, ** p < 0.01, *** p < 0.001 compared to alloxan. ++ p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: alloxan, physical alteration: endocrine pancreas chemical treatment by environment: ginsenoside C-K, physical alteration: endocrine pancreas chemical treatment by environment: ginsenoside C-K, physical alteration: endocrine pancreas chemical treatment by environment: alloxan, physical alteration: endocrine pancreas chemical treatment by environment: diazoxide, physical alteration: endocrine pancreas chemical treatment by environment: alloxan, physical alteration: endocrine pancreas
Observed In:	endocrine pancreas
Stage:	Day 5

Phenotype Detail

Acknowledgments

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