FIGURE

Fig. 4

ID

ZDB-FIG-170301-18

Publication

Nam et al., 2017 - Enhanced antidiabetic efficacy and safety of compound K⁄β-cyclodextrin inclusion complex in zebrafish

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Fig. 4

The effects of 5μM compound K (CK) and β-cyclodextrin included in compound K (CD-CK) in alloxan-induced pancreatic islet-damaged zebrafish. (A) The size change in the pancreatic islets in each group. (B) Fluorescence intensity analysis in the pancreatic islets of zebrafish. (C) Representative final pancreatic islet images of the normal (NOR), alloxan (AX), β-cyclodextrin (β-CD), glimepiride (GLM), CK, and CD-CK groups. The pancreatic islets are stained with 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose. The white arrow indicates the location of pancreatic islet. Scale bar = 100 μm. ^#p < 0.05 and ^###p < 0.001, compared to the normal group. * p < 0.05, ** p < 0.01, and *** p < 0.001, compared to the alloxan group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: alloxan, physical alteration: endocrine pancreas chemical treatment by environment: alloxan, physical alteration: endocrine pancreas chemical treatment by environment: ginsenoside C-K, physical alteration: endocrine pancreas chemical treatment by environment: ginsenoside C-K, physical alteration: endocrine pancreas chemical treatment by environment: alloxan, physical alteration: endocrine pancreas
Observed In:	endocrine pancreas
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Ginseng Res