FIGURE

Fig. 6

ID

ZDB-FIG-170208-14

Publication

Bielczyk-Maczyńska et al., 2015 - The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish

Other Figures

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Fig. 6

Ultrastructural studies of caudal hematopoietic tissue (CHT) in nol9^{sa1022/sa1022} larvae.

(A) Schematic representation of a transversal section in the CHT region of a 120 hpf zebrafish, dorsal up. NT–neural tube, NC–notochord, M—myotome, CA–caudal artery, CHT–caudal hematopoietic tissue, CV–caudal vein. (B-C) A low-magnification TEM image of the CHT from a nol9^+/+ (B, n = 2) and nol9^{sa1022/sa1022} (C, n = 2) larvae. Dashed line denotes the width of the CHT. Arrowheads denote mitochondrial profiles visible within myotomes (M). Asterisks denote extracellular matrix (ECM). (D-E) High magnification TEM image of cells present in the CHT of nol9^+/+ (D) and nol9^{sa1022/sa1022} (E) larvae. (F-G) High magnification TEM image of endothelial cells in the caudal vein of nol9^+/+ (F) and nol9^{sa1022/sa1022} (G) larvae. Arrow denotes vesicles visible in the cytoplasm of the endothelial cell, reminiscent of lipofuscin. E–endothelium. Scale bars: 2 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nol9^{sa1022/sa1022}
Observed In:	caudal vein endothelial cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

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