Fig. S1 A
NgAgo based fabp11a gene knockdown caused eye developmental defects in zebrafish. (A, A') Microscopy analysis of eyes infabp11a FW-guide DNA 2 and NgAgo-2nls mRNA coinjected embryos, lateral view. Red arrowheads indicate small developmental abnormal eyes. (B, C) Microscopy analysis of eyes in fabp11a FW-guide DNA 2 and NgAgo-2nls mRNA coinjected embryos, ventral view. Red arrowhead indicates relative normal eye. Green arrowhead indicates small developmental abnormal eye. (D) Relative mRNA levels of zebrafish fabp11a in 18 and 24 hpf control and ta FW-guide DNA 2 and NgAgo-2nls mRNA coinjected embryos. T-test; ****, P<0.0001. |