PUBLICATION

NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish

Authors
Qi, J., Dong, Z., Shi, Y., Wang, X., Qin, Y., Wang, Y., Liu, D.
ID
ZDB-PUB-161113-14
Date
2016
Source
Cell Research   26(12): 1349-1352 (Journal)
Registered Authors
Dong, Zhangji, Liu, Dong, Qi, Jialing, Qin, Yinyin, Shi, Yunwei, Wang, Xin
Keywords
none
MeSH Terms
  • Eye/embryology*
  • Eye/pathology
  • Gene Editing*
  • Humans
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Base Sequence
  • Fatty Acid-Binding Proteins/deficiency*
  • Fatty Acid-Binding Proteins/genetics
  • Eye Abnormalities/genetics*
  • Gene Expression Regulation, Developmental
  • Zebrafish Proteins/deficiency*
  • Zebrafish Proteins/genetics
  • Argonaute Proteins/genetics
  • Argonaute Proteins/metabolism*
  • INDEL Mutation
  • Animals
  • Gene Knockdown Techniques*
(all 18)
PubMed
27834346 Full text @ Cell Res.
Abstract
Genes / Markers
Figures
Figure Gallery (10 images)
Show all Figures
Expression
Phenotype
Fish Conditions Stage Phenotype Figure
WT + CRISPR1-fabp4astandard conditionsLong-pec
WT + CRISPR1-fabp4astandard conditionsLong-pec
WT + CRISPR1-fabp4astandard conditionsLong-pec
WT + CRISPR1-fabp4astandard conditionsLong-pec
WT + MO2-fabp4astandard conditionsLong-pec
1 - 5 of 5
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Mutations / Transgenics
Allele Construct Type Affected Genomic Region
s843TgTransgenic Insertion
    s916TgTransgenic Insertion
      1 - 2 of 2
      Show
      Human Disease / Model
      No data available
      Sequence Targeting Reagents
      Target Reagent Reagent Type
      fabp4aCRISPR1-fabp4aCRISPR
      fabp4aCRISPR2-fabp4aCRISPR
      fabp4aMO2-fabp4aMRPHLNO
      flt1MO3-flt1MRPHLNO
      1 - 4 of 4
      Show
      Fish
      Fish
      WT
      WT + CRISPR1-fabp4a
      WT + MO2-fabp4a
      1 - 3 of 3
      Show
      Antibodies
      No data available
      Orthology
      No data available
      Engineered Foreign Genes
      Marker Marker Type Name
      EGFPEFGEGFP
      mCherryEFGmCherry
      1 - 2 of 2
      Show
      Mapping
      No data available
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      Citation
      Qi, J., Dong, Z., Shi, Y., Wang, X., Qin, Y., Wang, Y., Liu, D. (2016) NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish. Cell Research. 26(12):1349-1352.