FIGURE

Fig. 8

ID
ZDB-FIG-160819-48
Publication
Dupret et al., 2016 - The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging
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Fig. 8

Phenotype of 12 month-old pcgf1-/- mutants.

(A) Pictures of 12 month-old pcgf1+/+ and pcgf1-/- fish. Note that both male and female pcgf1-/- fish exhibit mild spinal curvature. (B) Measurements of the spinal curvature score in 12 month-old fish from the pcgf1+/+ and pcgf1-/- populations. Statistical significance was assessed by Student t-test analysis and significance expressed as the value of p. (C) Senescence-associated β-galactosidase (SA-β-Gal) activity in 12 month-old zebrafish. Whole body staining of SA-β-Gal activity in pcgf1+/+ and pcgf1-/- fish harboring a spinal curvature are compared. (D) Quantification of SA-β-Gal activity in pcgf1+/+ and pcgf1-/- fish. Blue pixels obtained by whole body staining of SA-β-Gal activity were quantified in the trunk area between the operculum and the dorsal and anal fins by Adobe Photoshop and plotted using Prism (GraphPad). Error bars indicate ± SD.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Adult

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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