ZFIN ID: ZDB-FIG-160809-17
de Bruin et al., 2016 - Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo. Nucleic acids research   44(8):3549-66 Full text @ Nucleic Acids Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
GFP e2f8hu6024/+ ; js12Tg ; e2f7hu6023/hu6023 standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
e2f8hu6024/hu6024 ; e2f7hu6023/hu6023 ; js12Tg standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
js12Tg standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
js12Tg + MO1-e2f7 + MO1-e2f8 standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
js12Tg + MO3-hif1ab standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
nrp1ahu10012/hu10012 ; js12Tg standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
nrp1ahu10012/hu10012 ; js12Tg + MO1-e2f7 + MO1-e2f8 standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
nrp1ahu10012/hu10012 ; js12Tg + MO3-hif1ab standard conditions Long-pec motor neuron axon IFL
Long-pec trunk motor neuron IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
e2f8hu6024/+ ; js12Tg ; e2f7hu6023/hu6023 standard conditions Long-pec motor neuron axon guidance decreased process quality, abnormal
Long-pec motor neuron axon truncated, abnormal
e2f8hu6024/hu6024 ; e2f7hu6023/hu6023 ; js12Tg standard conditions Long-pec motor neuron axon guidance decreased process quality, abnormal
Long-pec motor neuron axon truncated, abnormal
js12Tg + MO1-e2f7 + MO1-e2f8 standard conditions Long-pec motor neuron axon guidance decreased process quality, abnormal
Long-pec motor neuron axon truncated, abnormal
js12Tg + MO3-hif1ab standard conditions Long-pec motor neuron axon guidance decreased process quality, abnormal
Long-pec motor neuron axon truncated, abnormal
nrp1ahu10012/hu10012 ; js12Tg standard conditions Long-pec motor neuron axon guidance process quality, normal
Long-pec motor neuron axon shape, normal
nrp1ahu10012/hu10012 ; js12Tg + MO1-e2f7 + MO1-e2f8 standard conditions Long-pec motor neuron axon guidance decreased process quality, ameliorated
Long-pec motor neuron axon truncated, ameliorated
nrp1ahu10012/hu10012 ; js12Tg + MO3-hif1ab standard conditions Long-pec motor neuron axon guidance decreased process quality, ameliorated
Long-pec motor neuron axon truncated, ameliorated
Acknowledgments:
ZFIN wishes to thank the journal Nucleic acids research for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Nucleic Acids Res.