ZFIN ID: ZDB-FIG-160720-5
Jain et al., 2016 - Hypoxia as a therapy for mitochondrial disease. Science (New York, N.Y.)   352(6281):54-61 Full text @ Science
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage: Day 4
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Long-pec to Days 7-13

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP sh144Tg control Day 4 anatomical structure IFL
sh144Tg chemical treatment: roxadustat Day 4 anatomical structure IFL
ldha WT control Day 4 anatomical structure ISH
WT chemical treatment: roxadustat Day 4 anatomical structure ISH
slc2a1a WT control Day 4 anatomical structure ISH
WT chemical treatment: roxadustat Day 4 anatomical structure ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment: antimycin A Long-pec - Pec-fin whole organism decreased life span, abnormal
Day 4 - Days 7-13 whole organism decreased life span, abnormal
WT chemical treatment: roxadustat Day 4 anatomical structure ldha expression increased amount, abnormal
Day 4 anatomical structure slc2a1a expression increased amount, abnormal
WT chemical treatment: antimycin A Day 4 - Days 7-13 whole organism decreased life span, ameliorated
sh144Tg chemical treatment: roxadustat Day 4 anatomical structure EGFP expression increased amount, abnormal
vhlhu2117/hu2117 chemical treatment: antimycin A Long-pec - Pec-fin whole organism decreased life span, ameliorated
Full text @ Science