Gene

ldha

ID
ZDB-GENE-991026-5
Name
lactate dehydrogenase A4
Symbol
ldha Nomenclature History
Previous Names
  • ldha1 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable L-lactate dehydrogenase activity. Acts upstream of or within response to hypoxia. Predicted to be located in cytoplasm. Is expressed in cardiovascular system; gill; muscle; and nervous system. Orthologous to several human genes including LDHA (lactate dehydrogenase A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ldha Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Glycogen storage disease XI 612933
Associated With ldha Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018177 L-lactate dehydrogenase, active site
Domain IPR001236 Lactate/malate dehydrogenase, N-terminal
Domain IPR022383 Lactate/malate dehydrogenase, C-terminal
Family IPR001557 L-lactate/malate dehydrogenase
Family IPR011304 L-lactate dehydrogenase
Homologous_superfamily IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal Lactate/malate dehydrogenase, C-terminal Lactate/malate dehydrogenase, N-terminal L-lactate dehydrogenase L-lactate dehydrogenase, active site L-lactate/malate dehydrogenase NAD(P)-binding domain superfamily
UniProtKB:Q7ZVJ4 333
UniProtKB:Q9PVK5 333
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations