FIGURE

Fig. 1

ID

ZDB-FIG-160603-12

Publication

Smith et al., 2016 - Radial glia inhibit peripheral glial infiltration into the spinal cord at motor exit point transition zones

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Fig. 1

Peripheral and central myelinating glia are segregated at the MEP. A: Schematic of a zebrafish larvae with the brain and spinal cord labeled in red. Boxed region shows the spinal motor nerve roots, which are magnified in B. B: Schematics of spinal motor roots at 24, 48, and 72 hpf showing motor axons (red), PNS glia (green) and CNS glia (yellow). Images of Tg(sox10:eos);Tg(olig2:dsred) embryos at (C) 24, (D) 48 (E), and 72 hpf. Lateral and cross section (90°) views are shown. Arrows denote peripheral sox10⁺ glia and arrowheads denote central sox10⁺/olig2⁺ OPCs. Asterisks at 48 and 72 hpf denote Eos expression in spinal cord neurons. Dotted lines represents spinal cord boundary. Scale bar, 25 µm.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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