ZFIN ID: ZDB-FIG-160505-23
Xing et al., 2015 - A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. The Journal of neuroscience : the official journal of the Society for Neuroscience   35:14794-808 Full text @ J. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Conditions:
Anatomical Terms:
Stage Range: Prim-25 to Protruding-mouth
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Prim-25 to Protruding-mouth

Fig. 8 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
efnb2a Ab1-efnb2 WT standard conditions Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon IHC
Ab1-efnb2 WT chemical treatment: fluoxetine Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon IHC
Ab1-efnb2 WT hypoxia, chemical treatment: fluoxetine Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon IHC
Ab1-efnb2 WT hypoxia Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon IHC
EGFP zc69Tg standard conditions Long-pec commissure of the tract of the commissure of the caudal tuberculum axon IHC
zc69Tg chemical treatment: fluoxetine Long-pec commissure of the tract of the commissure of the caudal tuberculum axon IHC
zc69Tg hypoxia, chemical treatment: fluoxetine Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum axon IHC
zc69Tg hypoxia Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum axon IHC
tph2 WT standard conditions Prim-25 raphe nucleus serotonergic neuron ISH
Prim-25 raphe nucleus serotonergic neuron RTPCR
Long-pec raphe nucleus serotonergic neuron RTPCR
WT hypoxia Prim-25 raphe nucleus serotonergic neuron RTPCR
Long-pec raphe nucleus serotonergic neuron RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-elavl IHC WT standard conditions Long-pec raphe nucleus serotonergic neuron
IHC WT hypoxia Long-pec raphe nucleus serotonergic neuron
Ab2-serotonin IHC WT standard conditions Long-pec raphe nucleus serotonergic neuron
IHC WT hypoxia Long-pec raphe nucleus serotonergic neuron
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment: fluoxetine Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon efnb2a expression decreased amount, abnormal
WT hypoxia, chemical treatment: fluoxetine Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon efnb2a expression amount, ameliorated
WT hypoxia Prim-25 commissure of the tract of the commissure of the caudal tuberculum axon efnb2a expression increased amount, abnormal
Prim-25 raphe nucleus serotonergic neuron tph2 expression decreased amount, abnormal
Long-pec raphe nucleus serotonergic neuron tph2 expression decreased amount, abnormal
Long-pec raphe nucleus serotonergic neuron ab2-serotonin labeling decreased amount, abnormal
zc69Tg chemical treatment: fluoxetine Long-pec commissure of the tract of the commissure of the caudal tuberculum commissural neuron axon guidance increased process quality, abnormal
Long-pec commissure of the tract of the commissure of the caudal tuberculum has extra parts of type commissure of the tract of the commissure of the caudal tuberculum axon, abnormal
zc69Tg hypoxia, chemical treatment: fluoxetine Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum commissural neuron axon guidance process quality, ameliorated
Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum has number of commissure of the tract of the commissure of the caudal tuberculum axon, ameliorated
zc69Tg hypoxia Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum commissural neuron axon guidance decreased process quality, abnormal
Protruding-mouth commissure of the tract of the commissure of the caudal tuberculum has fewer parts of type commissure of the tract of the commissure of the caudal tuberculum axon, abnormal
Full text @ J. Neurosci.