FIGURE

Fig. 6, S1

ID
ZDB-FIG-160413-10
Publication
Agarwala et al., 2015 - Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish
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Fig. 6, S1

Loss of Yap1 in MZamotl2a-/-;MZyap1-/- embryos supresses increased pLLP cell number resulting from loss of Amotl2a in MZamotl2a-/- embryos.

The mutation of Yap1-binding domains in Amotl2a does not render it unstable. MIP of Z-stacks of pLLP in cldnb:gfp embryos with the indicated genotype (AD). (E) Corresponding boxplot comparing pLLP cell counts. (F) Western blot showing the stability of wild-type Amotl2a, Amotl2aFL (lane2) and Amotl2a forms carrying both PPEA-LATA (lane3) and single PPEA and LATA (lanes 4 and 5), respectively. α-tubulin staining shows equal protein loading (Figure 6—source data 4).

Expression Data
Gene:
Fish:
Anatomical Term:
Stage: Prim-15

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Prim-15

Phenotype Detail
Acknowledgments
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