FIGURE

Fig. S11

ID
ZDB-FIG-160311-31
Publication
Guo et al., 2016 - Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation
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Fig. S11

Body curvature in embryos with lbx1b expressed under the control of the GATA2 minimal promoter and an lbx1b enhancer.

(A) Dorsal views of live embryos at 48 hpf. Body curvature was observed in zebrafish injected with GATA2-1b:lbx1b (lbx1b), but not in those injected with GATA2-1b:MCS (ctrl). The scale bar represents 500 µm. (B) Quantitative analysis of body curvature (cur) in 48 hpf embryos. The incidence of body curvature was significantly increased in lbx1b embryos (ctrl, 5%, n = 83; lbx1b, 46%, n = 94. p < 0.01). Scale bar in (A): 500 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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