Fig. 7
- ID
- ZDB-FIG-151221-8
- Publication
- Chua et al., 2015 - Tumor-specific signaling to p53 is mimicked by Mdm2 inactivation in zebrafish: insights from mdm2 and mdm4 mutant zebrafish
- Other Figures
- All Figure Page
- Back to All Figure Page
Accumulation of mutant p53 protein in tumors of p53M214K/M214K fish. Adult p53M214K/M214K zebrafish that were observed to have developed tumors in the eye and trunk were sacrificed, fixed and embedded in paraffin for histological analysis with the p53-5.1 hybridoma supernatant. The sections were counterstained with hematoxylin and imaged under brightfield. (a) Normal eye from a p53M214K/M214K fish ( × 10 magnification). (b) Tumor in the eye of a p53M214K/M214K fish ( × 10 magnification). (c) Tumor in the eye of a p53M214K/M214K fish ( × 40 magnification). (d) Tumor in the trunk of a p53M214K/M214K fish ( × 40 magnification). P, pigmentation of eye lens. |
Gene: | |
---|---|
Antibody: | |
Fish: | |
Anatomical Terms: | |
Stage: | Adult |