FIGURE

Fig. 5

ID

ZDB-FIG-150420-37

Publication

Deml et al., 2015 - Mutations in MAB21L2 Result in Ocular Coloboma, Microcornea and Cataracts

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Fig. 5

Summary of TUNEL assays in zebrafish wild-type and mab21l2 mutant embryos.

TUNEL results in 24-hpf wild-type (A-B), mab21l2^Q48Sfs*5 embryos (C-D) and mab21l2^R51_F52del mutants (E-F) are shown. An increase in TUNEL staining was observed in both mab21l2 mutants with remarkably high levels in the mab21l2^Q48Sfs*5 embryos, particularly in the lens and ventral retina (C-D), and moderately increased levels in the mab21l2^R51_F52del embryos (E-F); arrowheads indicate sites of increased TUNEL staining in the eye and brain; le, lens; r, retina.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mab21l2^mw701/mw701 mab21l2^mw702/mw702
Observed In:	lens apoptotic process retina apoptotic process
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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