FIGURE

Fig. 2

ID

ZDB-FIG-150408-29

Publication

Merkes et al., 2015 - Ewing Sarcoma Ewsa Protein Regulates Chondrogenesis of Meckel's Cartilage through Modulation of Sox9 in Zebrafish

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Fig. 2

4 dpf MZ ewsa/ewsa mutants display an aberrant angle of Meckel’s cartilage and palatoquadrate.

A. Lateral views (anterior to the left) of wt/wt (left) and MZ ewsa/ewsa (right) and ventral views of adult zebrafish. The calcified bones were visualized by alizarin red staining. B. Lateral views (anterior to the left) of (a) wt/wt and (b) MZ ewsa/ewsa and ventral views of (c) wt/wt and (d) MZ ewsa/ewsa chondrocytes from 4 dpf zebrafish embryos visualized with alcian blue. (e and f) Angle formed by Meckel’s cartilage showing that the palatoquadrate is wider in the MZ ewsa/ewsa mutant than wt/wt at 4 dpf and 7 dpf. bh: basihyal, d: dentary, m: Meckel’s cartilage, pq: palatoquadrate, ch: ceratohyal, cb: ceratobranchial.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ewsr1a^{zm00260171Tg/zm00260171Tg}
Observed In:	basihyal bone dentary mandibular arch skeleton Meckel's cartilage palatoquadrate cartilage
Stage Range:	Day 4 to Adult

Phenotype Detail

Acknowledgments

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