FIGURE

Fig. S2

ID

ZDB-FIG-150313-42

Publication

Gutzman et al., 2015 - Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis

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Fig. S2

Whole embryo phenotypes for morpholino injected embryos. Single cell embryos were injected with (A,B) 4ng control MO + 4ng p53 MO, (C,D) 4ng myh9a MO, (E,F) 3ng myh9b MO + 3ng p53 MO, or (G,H) 3ng myh10 MO. Live embryos were imaged using brightfield microscopy at 24 ss and at 48 hpf as indicated. myh9a morphants did not demonstrate any obvious phenotypes at the times imaged. For myh9b and myh10 morphants, representative mild phenotypes are shown. myh9b morphants demonstrated somite defects, abnormal tail curvature, pigmentation defects, heart abnormalities, slight edema, and abnormal eye and ear formation. myh10 morphants had abnormal body axis curvature, heart abnormalities, slight edema, and abnormal eye development.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-myh10 AB + MO3-myh9a
Knockdown Reagents:	MO1-myh10 MO3-myh9a
Observed In:	eye heart pigmentation post-vent region somite whole organism
Stage Range:	20-25 somites to Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 397(1), Gutzman, J.H., Sahu, S.U., Kwas, C., Non-muscle myosin IIA and IIB differentially regulate cell shape changes during zebrafish brain morphogenesis, 103-15, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.