FIGURE

Fig. 2

ID

ZDB-FIG-150304-21

Publication

Tsuruwaka et al., 2015 - Loss of wwox expression in zebrafish embryos causes edema and alters Ca(2+) dynamics

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Fig. 2

Knockdown of wwox induced pericardial edema and reduced eye formation in embryos during the long-pec stage at 48 h post fertilization.

Arrows indicate edema; (A) Upper, A bright-field image of a (i) wild-type embryo; (ii) wwox negative-control MO-injected embryo; and (iii) wwox MO-injected embryo; Lower, fluorescence image of the upper panel. (B) A wwox siRNA-injected embryo. (C) A wwox rescued MO-injected embryo (upper, bright-field image; lower, fluorescence image). (D) A wwox rescued siRNA-injected embryo. (E) Quantification of body lengths and eye sizes of long-pec embryos; 30 embryos were examined in three independent experiments and data are expressed as means ± SEM (^∗∗p < 0.01); WT, wildtype; Scale bars, 250 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-wwox
Knockdown Reagent:	MO1-wwox
Observed In:	eye pericardium whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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